Description

Donepezil

 

Donepezil, a hexa-oxypyridine oxide, is a second-generation specific reversible central acetylcholinesterase (AChE) inhibitor with little effect on peripheral AChE. By inhibiting AChE activity, this product slows down the breakdown of acetylcholine (ACh) in the synaptic cleft, thereby increasing the content of ACh and improving the cognitive function of patients with Alzheimer’s disease (AD). The strength of inhibiting acetylcholinesterase activity is 570 times higher than that of butyrylcholinesterase, and it has high selectivity. Oral administration of 10 mg/kg can inhibit the cholinesterase in the brain in a dose-dependent manner.

 

More About Donepezil：

Molecular formula: C24H29NO3
Molecular weight: 379.49
CAS no.:120014-06-4
EINECS no. : 601-651-9

 

Specification：

AppearanceWhite crystal powder
Melting point207°C
Content%98%-101%
Density2.931 mg/L

 

Use Of Donepezil:

 

Donepezil hydrochloride-water is a centrally reversible acetylcholinesterase inhibitor.

 

Package Of Donepezil：

25KG/drum

Storage:The warehouse is ventilated and dried at low temperature; it is stored separately from oxidants and food additives.